Taladalfil/Sildenafil

Tadalafil/Sildenafil compound is a custom-prepared medication that combines the effects of both drugs to enhance erectile function by increasing blood flow to the penis through the inhibition of phosphodiesterase type 5 (PDE5).

Dosage Form:

Oral

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Medicine information for The Chemist Shops Taladalfil/Sildenafil

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How it works

The combination of tadalafil and sildenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which increases blood flow to the penis and facilitates stronger and longer-lasting erections.

Side Effects

Common side effects of the tadalafil/sildenafil combination include headaches, flushing, indigestion, nasal congestion, back pain, and visual disturbances.

Storage

Store at room temperature (68–77°F / 20–25°C). Do not refrigerate or freeze.

Pregnancy Information

Tadalafil and sildenafil are classified under Pregnancy Category B by the FDA, indicating that animal studies have shown no risk to the fetus, but there are no adequate and well-controlled studies in pregnant women.

Drug Interactions

Absolute contraindication with nitrates (nitroglycerin, isosorbide dinitrate/mononitrate) → life-threatening hypotension. Alpha-blockers (tamsulosin, doxazosin, prazosin) → additive hypotension. Ritonavir, ketoconazole, itraconazole, clarithromycin (CYP3A4 inhibitors) → ↑ PDE5 inhibitor levels → ↑ risk of hypotension, priapism, vision changes. Rifampin, carbamazepine, phenytoin (CYP3A4 inducers) → ↓ PDE5 effectiveness. Alcohol → worsens dizziness, hypotension.

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