Gastroenterology
Anorectal Therapy

Nifedipine Rectal Cream

Compounded topical cream used for management of anal fissures by decreasing sphincter pressure and improving healing; Dispensed in tube with tip.

Dosage Form:
Cream
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How it works

Nifedipine blocks calcium channels in smooth muscle leading to relaxation of the internal anal sphincter and improved blood flow.

Side Effects

Possible side effects include local irritation, flushing, headache, dizziness, or mild burning.

Storage

Store at room temperature (68–77°F / 20–25°C). Do not refrigerate or freeze.

Pregnancy Information

May be considered in pregnancy if prescribed by a healthcare provider when benefits outweigh risks.

Drug Interactions

May interact with other antihypertensive drugs, calcium channel blockers, or medications that lower blood pressure.

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